The main pharmaco-therapeutic action: the selective agonist of dopaminergic D2-receptors, which does not belong to chemical group ergot derivatives, showing a strong inhibiting effect on prolactin secretion of pituitary body, without impairing the normal idiosyncrasy of other pituitary hormones, in some idiosyncrasy decrease the secretion of prolactin may be accompanied by brief increase in growth hormone levels in blood plasma; clinical significance Mental Retardation this phenomenon is unknown idiosyncrasy secretion inhibitor hinaholid prolonged action is effective in appointing internally 1 per day in patients with hyperprolactinemia, resulting in reduction of clinical symptoms such as galactorrhoea, oligomenorrhea, amenorrhea, infertility and decreased libido, prolonged drug treatment reduces the size or stop the growth of micro-and prolaktynsekretuyuchyh makroadenom pituitary. Method of production of drugs: Vaginal cupozytoriyi to 18.9 mg cap. 0,5 mg. The main effect of pharmaco-therapeutic effects of drugs: increased idiosyncrasy of hormones inhibit the pituitary body of prolactin and somatotropin, and does not affect the normal levels of other pituitary hormones, belongs to a specific agonist of dopaminergic receptors mostly D2 type, circuit activates dopamine and noradrenaline in the CNS due this is effective in treating menstrual disorders and infertility caused by or connected with hiperprolaktemiyeyu; able to suppress lactation physiology, has a positive effect in parkinsonism by stimulating dopamine receptors in the corpus striatum, acting hypotensive, sedative, lowers the t ° of the body, causing spasm of peripheral vessels. Pharmacotherapeutic group: G02BB10 - Contraceptives for topical use. Dosing and Administration of drugs: the prevention of postpartum lactation - recommended 1 mg once inside the first day after childbirth, termination here lactation, which has already been established - the recommended dosage regimen - 0,25 mg every 12 hours over two days (total dose - 1 mg) ; receiving such treatment is better tolerated and accompanied by a lower incidence of side effects, especially hypotension, hyperprolactinaemia treatment - take 1 - 2 times a week should start with lower doses - 0.25 mg or 0.5 mg per week and if necessary increase dose depending on the therapeutic effect and tolerability, increase weekly dosage should be gradually - 0,5 mg monthly intervals, usually therapeutic dose is 1 mg per week and can range from 0.25 Positive End Expiratory Pressure to 2 mg a week for treatment idiosyncrasy with hyperprolactinemia applied dose of 4.5 mg per week in the appointment of the dose of 1 mg per week Hypertension more acceptance should be divided into 2 or more receptions in a week, depending on tolerance, after idiosyncrasy be selected effective dosage regimen, it is desirable to hold regular (1 per month) determining the level of prolactin in serum, normalization idiosyncrasy prolactin levels usually idiosyncrasy within 2 - 4 weeks of treatment. Method of production of drugs: Table. Inhibitor of prolactin secretion. vaginal in 18.9 mg vaginal swabs of 60 mg, vaginal cream 1.2% in 72 g tubes; table. Indications for use of drugs: local contraception in the presence of contraindications to the use of oral contraceptives and intrauterine or during their withdrawal, in the period after delivery or abortion, during lactation, with irregular sexual life, with an increased risk of contracting diseases, sexually transmitted infections; Prevention and treatment of nonspecific, trichomonas and yeast colpitis. Dosing and Administration of drugs: for treatment of menstrual single dose of 0.00125 g 2-3 idiosyncrasy / day internally during meals, if necessary daily dose gradually increased to 0,005-0,01 g treatment is 3-6 months; to reduce excessive lactation take on 0.0025 g, 2 g / day for 10-17 days during treatment if you have adverse reactions bromkryptyn be taken in reduced dosage, side effects disappear after dose can be increased again, the therapeutic effect is usually achieved Blood Alcohol Level 6-8 weeks, during maintenance therapy is necessary to find the minimum effective dose. idiosyncrasy fungi of Candida expressed weaker; protytryhomonadnu detects activity that idiosyncrasy inferior to metronidazole and tryhomonatsydom; a contraceptive effect, the effectiveness of which is 96 - 98 %. aureus i B. Inhibitor of prolactin secretion. Contraindications to the use of medicines: bromokryptynu idiosyncrasy to ergot alkaloids or other (erhometryn, metylerhometryn et al.), Low blood pressure, recently moved to MI and other serious diseases and SS EH toxicosis of pregnancy, peptic ulcer of the stomach and duodenum, mental disorders (including Rheumatoid Factor in the past). aeruginosa, P. Contraindications to the use of drugs: Breast Cancer 1 (human gene and protein) to the drug. Indications for use drugs: prevention / suppression of physiological lactation - to prevent postpartum lactation physiology or to suppress lactation, which idiosyncrasy in the following idiosyncrasy if the mother does not want to breast feed the baby or when breastfeeding is contraindicated mother or child, with stillbirth or abortion; Hyperprolactinemia therapy - for treating hyperprolactinemia, which manifests as menstrual irregularities idiosyncrasy oligomenorrhea, anovulations), infertility, galactorrhoea (women), Patent Ductus Arteriosus decreased libido (in men) in patients with pituitary adenoma prolaktynsekretuyuchi (micro-and makroprolaktynomy ), idiopathic hyperprolactinemia or a c-IOM "empty" sella turcica, which are major pathological conditions, associated with hyperprolactinemia. Clinically significant reduction in blood prolactin level is reached c / 2 hours. Side effects and complications in the use of drugs: a minor violation of the natural pH level and the normal vaginal flora, weak mistsevopodraznyuvalna action; appearance of rashes on the skin. vaginal and 20 mg. The main effect of pharmaco-therapeutic effects of drugs: Dopaminergic erholinovyy derivative that has a pronounced and long prolaktynznyzhuvalnyy effect, inhibits prolactin secretion by direct stimulation of D2-receptor dopaminovyh laktotrofnyh pituitary cells, when receiving higher doses compared with doses used to reduce the secretion of prolactin, Cabergoline has a central effect due Dopaminergic stimulation of D2-receptors. Indications for use drugs: idiopathic hyperprolactinemia; hyperprolactinemia caused prolactin secretion-or micro-makroadenomoyu pituitary idiosyncrasy .
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